Summer Research Internship
Project 27 Antibody Isolation from a Yeast Display Library

Contact Information

Prof. Zhiping  Xie 



Project Description and Objectives

Antibodies are indispensable tools in modern biomedical research and applications. The yeast display method enables the selection and production of an antibody of interest in one single host system. It avoids the potential complications of different protein post-translational modifications when antibody isolation and production are performed in two hosts. The use of yeast also provides clear advantages in production cost and biosafety.


Eligibility Requirements

  • The interested student should have a basic knowledge of biology or biomedical sciences;
  • Prior experiences in molecular cloning, protein expression and purification would be preferred.


Main Tasks

Clone, express and purify protein of interest.

Label protein of interest and isolate yeast cells displaying binding antibodies.

Purify antibodies and verify binding specificity.



Lab: N/A


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