Prof. Yongting Wang
Prof. Yaohui Tang
Project Description and Objectives
Stem cells are being tested in several clinical trials for the treatment of ischemic stroke. Gene engineering of stem cells takes advantage of the stem cells not only as a therapeutic moiety but also as a factory and cargo for the gene product. In addition, gene modification of stem cells can also augment the survival and function of the transplanted stem cells. Previously, our lab had identified that bFGF plays a key role in tissue protection after ischemic insult. In this project, we aim to investigate the potential of bFGF gene engineered endothelial progenitor cells in treating ischemic injury. The students will join a team of graduate students and research faculty members. Techniques used in this project will include but not limit to stem cell culture, exosome preparation, animal surgery, and data analysis.
Must be at least in their sophomore year.
Skills desirable but not required: cell culture, molecular cloning.
Attend weekly lab meetings and carry out experiments.
Give two research presentations, (one on literature review, one on research progress).
Finish a research report.